FAIR assessment of Disease Maps fosters open science and scientific crowdsourcing in systems biomedicine

The Disease Maps Project focuses on the development of disease-specific comprehensive structured knowledge repositories supporting translational medicine research. These disease maps require continuous interdisciplinary collaboration and should be reusable and interoperable. Adhering to the Findable, Accessible, Interoperable and Reusable (FAIR) principles enhances the utility of such digital assets. We used the RDA FAIR Data Maturity Model and assessed the FAIRness of the Molecular Interaction NEtwoRk VisuAlization (MINERVA) Platform. MINERVA is a standalone webserver that allows users to manage, explore and analyse disease maps and their related data manually or programmatically. We exemplify the FAIR assessment on the Parkinson's Disease Map (PD map) and the COVID-19 Disease Map, which are large-scale projects under the umbrella of the Disease Maps Project, aiming to investigate molecular mechanisms of the Parkinson's disease and SARS-CoV-2 infection, respectively. We discuss the FAIR features supported by the MINERVA Platform and we outline steps to further improve the MINERVA FAIRness and to better connect this resource to other ongoing scientific initiatives supporting FAIR in computational systems biomedicine.

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Publication Details

Journal
Scientific Data
Published
2025-05-23
DOI
https://doi.org/10.1038/s41597-025-05147-w
Citations
1
Primary Topic
Scientific Computing and Data Management
Type
article
Field-Weighted Citation Impact
4.17
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article

FAIR assessment of Disease Maps fosters open science and scientific crowdsourcing in systems biomedicine

Esther Thea Inau, Marek Ostaszewski, Alexander Mazein, Irina Balaur et al.
1 citations
Scientific Data
Scientific Computing and Data Management
4.17
article

FAIR assessment of Disease Maps fosters open science and scientific crowdsourcing in systems biomedicine

Esther Thea Inau, Marek Ostaszewski, Alexander Mazein, Irina Balaur, Reinhard Schneider, Adrien Rougny, Danielle Welter, Venkata Satagopam, Soumyabrata Ghosh, Dagmar Waltemath
article en
1 citations

Abstract

The Disease Maps Project focuses on the development of disease-specific comprehensive structured knowledge repositories supporting translational medicine research. These disease maps require continuous interdisciplinary collaboration and should be reusable and interoperable. Adhering to the Findable, Accessible, Interoperable and Reusable (FAIR) principles enhances the utility of such digital assets. We used the RDA FAIR Data Maturity Model and assessed the FAIRness of the Molecular Interaction NEtwoRk VisuAlization (MINERVA) Platform. MINERVA is a standalone webserver that allows users to manage, explore and analyse disease maps and their related data manually or programmatically. We exemplify the FAIR assessment on the Parkinson's Disease Map (PD map) and the COVID-19 Disease Map, which are large-scale projects under the umbrella of the Disease Maps Project, aiming to investigate molecular mechanisms of the Parkinson's disease and SARS-CoV-2 infection, respectively. We discuss the FAIR features supported by the MINERVA Platform and we outline steps to further improve the MINERVA FAIRness and to better connect this resource to other ongoing scientific initiatives supporting FAIR in computational systems biomedicine.

Scientific DataVol. 12(1)
University of Luxembourg (LU), Universitätsmedizin Greifswald (DE)
Partnerships for the goals
Openalex Percentile: Top 6%
Scientific Computing and Data Management
4.17
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