Monoterpene derivatives from the fruits of <i>Illicium simonsii</i>
Three previously undescribed monoterpene derivatives, illisimoncins A-C (<b>1</b>-<b>3</b>) and one undescribed 2-formylpyrrole alkaloid (<b>4</b>) were isolated from the fruits of <i>Illicium simonsii</i> together with five known monoterpenes (<b>5</b>-<b>9</b>). Structural elucidation of compounds <b>1</b>-<b>4</b> was elucidated through comprehensive spectroscopic analyses and their absolute configurations were determined by the dimolybdenum tetraacetate [Mo<sub>2</sub>(AcO)<sub>4</sub>]-induced ICD experiment and modified Mosher's method. Compounds <b>2</b> and <b>7</b> showed antiviral activities against Coxsackievirus B3 with IC<sub>50</sub> values of 57.74 and 23.24 µM, respectively.
Authors
- Shuang‐Gang Ma (ORCID: https://orcid.org/0000-0002-1065-154X)
- Shi‐Shan Yu (ORCID: https://orcid.org/0000-0002-0821-9029)
- Guo‐Zhu Su
- Yuhuan Li (ORCID: https://orcid.org/0000-0003-3725-3258)
- Xiaojing Wang (ORCID: https://orcid.org/0000-0002-4049-8822)
- Haiqiang Wang (ORCID: https://orcid.org/0000-0003-0487-3274)
- Mi Li
- Li Li (ORCID: https://orcid.org/0000-0001-9982-0460)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1080/10286020.2025.2504964
- Primary Topic
- Magnolia and Illicium research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China