Electrochemical Regioselective C-3 Alkoxycarbonylation of 2<i>H</i>-Indazoles
This study describes an efficient electrochemical synthetic method for C-3 alkoxycarbonylation of 2<i>H</i>-indazoles with carbazates under constant current in an undivided cell without the need for external oxidants or metal catalysts. This methodology exhibits broad functional group compatibility, affording the products with good yields. Easy scalability and drug diversification demonstrate the synthetic efficacy and applicability of this protocol.
Authors
- Duddu S. Sharada (ORCID: https://orcid.org/0000-0001-5861-4126)
- Jagadeesh Reddy Thondur
- Gedu Satyanarayana (ORCID: https://orcid.org/0000-0002-6410-5421)
- Punith S Gowda
Institutions
- Pondicherry University (IN)
- Indian Institute of Technology Hyderabad (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1021/acs.joc.5c00785
- Citations
- 4
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- Council of Scientific and Industrial Research, India
- Ministry of Education, India
- Science and Engineering Research Board