A Rare Case of Large Ovarian Thecoma Diagnosed Histopathologically Following Surgical Management in a Premenopausal Woman: A Case Report and Review of the Current Literature

Ovarian thecomas are rare sex cord-stromal tumors of the ovary. These tumors are estimated to account for 1% of all ovarian neoplasms. Thecomas are primarily composed of cells that resemble theca cells, which are involved in estrogen production. While thecomas are more frequently observed in postmenopausal women, they can also occur in premenopausal women. This report presents a rare case of an ovarian thecoma in a premenopausal woman and reviews the current literature on the topic. Herein we endeavor to contribute to the current body of knowledge and provide guidance to clinicians managing similar cases. Our patient is 43 years old and was diagnosed with an ovarian thecoma after she presented to our facility complaining of abdominal pain and abdominal distension. She underwent a total abdominal hysterectomy and unilateral salpingo-oophorectomy. Histopathological examination confirmed a benign thecoma. We demonstrate that it is crucial to consider this benign condition when evaluating solid ovarian tumors in premenopausal women.

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Publication Details

Journal
Clinical Case Reports
Published
2025-05-01
DOI
https://doi.org/10.1002/ccr3.70528
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

A Rare Case of Large Ovarian Thecoma Diagnosed Histopathologically Following Surgical Management in a Premenopausal Woman: A Case Report and Review of the Current Literature

Tecla Lyamuya, Alex Mremi, Bariki Lawrence Mchome, John Lugata et al.
Clinical Case Reports
Ovarian cancer diagnosis and treatment
article

A Rare Case of Large Ovarian Thecoma Diagnosed Histopathologically Following Surgical Management in a Premenopausal Woman: A Case Report and Review of the Current Literature

Tecla Lyamuya, Alex Mremi, Bariki Lawrence Mchome, John Lugata, Ashley Rapheal, Laetitia Makower, Julius Kaleshu
article en

Abstract

Ovarian thecomas are rare sex cord-stromal tumors of the ovary. These tumors are estimated to account for 1% of all ovarian neoplasms. Thecomas are primarily composed of cells that resemble theca cells, which are involved in estrogen production. While thecomas are more frequently observed in postmenopausal women, they can also occur in premenopausal women. This report presents a rare case of an ovarian thecoma in a premenopausal woman and reviews the current literature on the topic. Herein we endeavor to contribute to the current body of knowledge and provide guidance to clinicians managing similar cases. Our patient is 43 years old and was diagnosed with an ovarian thecoma after she presented to our facility complaining of abdominal pain and abdominal distension. She underwent a total abdominal hysterectomy and unilateral salpingo-oophorectomy. Histopathological examination confirmed a benign thecoma. We demonstrate that it is crucial to consider this benign condition when evaluating solid ovarian tumors in premenopausal women.

Clinical Case ReportsVol. 13(5)
University of Cambridge (GB), Kilimanjaro Christian Medical Centre (TZ)
Good health and well-being
Openalex Percentile: Top 84%
Ovarian cancer diagnosis and treatment
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A Rare Case of Large Ovarian Thecoma Diagnosed Histopathologically Following Surgical Management in a Premenopausal Woman: A Case Report and Review of the Current Literature — Tecla Lyamuya, Alex Mremi, et al. · Clinical Case Reports (2025) | TGRS Research Map | TGRS