Global Burden of Pancreatic Cancer Among Individuals Aged 15–59 Years in 204 Countries and Territories, 1990–2021: A Systematic Analysis for the GBD 2021 and Projections to 2045

High SDI regions exhibit concentrated PC burdens linked to lifestyle factors, whereas China's rising trends align with healthcare expansion and metabolic disease proliferation. Targeted interventions-smoking cessation, glycemic control, and weight management-are imperative to mitigate growing burdens in younger populations. This study highlights the urgent need for region-specific strategies to address evolving epidemiological challenges in PC prevention and control.