Detection of p53 aggregates in plasma of glioma patients
This study demonstrates the detection of p53 aggregates in liquid biopsies. Our findings highlight the potential of p53 aggregates as a novel biomarker for glioblastoma.
Authors
- Kevin Michael Brindle (ORCID: https://orcid.org/0000-0003-3883-6287)
- John S. H. Danial (ORCID: https://orcid.org/0000-0002-9882-8441)
- Emre Fertan (ORCID: https://orcid.org/0000-0002-0060-5806)
- David A. Klenerman (ORCID: https://orcid.org/0000-0001-7116-6954)
- Jeff Y. L. Lam (ORCID: https://orcid.org/0000-0001-7408-2342)
- Linda Julian (ORCID: https://orcid.org/0000-0001-5041-287X)
- Zengjie Xia (ORCID: https://orcid.org/0000-0002-5977-9691)
- Edward Fysh (ORCID: https://orcid.org/0000-0003-1126-3773)
- Dorothea Böken (ORCID: https://orcid.org/0009-0008-8443-4469)
- Matthaios Pitoulias (ORCID: https://orcid.org/0000-0002-9814-0604)
- Richard James Mair (ORCID: https://orcid.org/0000-0001-8235-5689)
- Zi-Wei Zhang (ORCID: https://orcid.org/0000-0002-2140-4886)
- Yunzhao Wu
- Renuka Chintapalli
- Gemma Tsang-Pells
Institutions
- University of Cambridge (GB)
- Cancer Research UK (GB)
- Cancer Research UK Cambridge Center (GB)
- UK Dementia Research Institute (GB)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1038/s43856-025-00918-3
- Citations
- 5
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Cancer Research UK
- Croucher Foundation