Synergistic Drivers of Vegetation Dynamics in a Fragile High-Altitude Basin of the Tibetan Plateau Using General Regression Neural Network and Geographical Detector

The internal response mechanism of vegetation change in fragile high-altitude ecosystems is pivotal for ecological stability. This study focuses on the Lhasa River Basin (LRB) on the Tibetan Plateau (TP), a typical high-altitude fragile ecosystem where vegetation dynamics are highly sensitive to climate change and human activities. Utilizing MODIS surface reflectance data (MOD09Q1), a general regression neural network (GRNN) was applied to create a 250 m resolution fractional vegetation cover (FVC) dataset from 2001 to 2022, whose accuracy was verified with field survey data. Through methods like the Theil–Sen Median trend analysis, Mann–Kendall significance test, Hurst exponent, and geographical detector, the collaborative mechanism of 14 driving factors was systematically explored. Key conclusions are as follows: (1) The FVC in the LRB evolved in stages, first decreasing and then increasing, with 46.71% of the basin area expected to show an improvement trend in the future. (2) Among natural factors, elevation (q = 0.480), annual mean potential evapotranspiration (q = 0.362), and annual mean temperature (q = 0.361) are the main determinants of FVC spatiotemporal variation. (3) In terms of human activities, land use type has the highest explanatory power (q = 0.365) for FVC. (4) The interaction of two factors on FVC is stronger than that of a single factor, with the elevation–land use interaction being the most significant (q = 0.558). These results deepen our understanding of the interactions among vegetation, climate, and humans in fragile high-altitude ecosystems and provide a scientific basis for formulating zoned restoration strategies on the TP.