An Integrated Analysis of Transcriptomic and Metabolomic Effects Reveals Insights into Stress Responses in Largemouth Bass (Micropterus salmoides) Under MS-222 (Tricaine Methanesulfonate) Exposure
These findings reveal that MS-222 anesthesia triggers organ-specific physiological adaptations through the differential regulation of metabolic and immune pathways, which provide multi-omics insights into the mechanistic basis of anesthetic responses in fish, highlighting distinct tissue strategies for managing chemical stress.
Authors
- De‐Yun Ma (ORCID: https://orcid.org/0000-0001-7337-5346)
- Haodong Yu
- Ping Gao (ORCID: https://orcid.org/0000-0001-6140-8796)
- Xuezhen Zhang (ORCID: https://orcid.org/0000-0002-8949-315X)
- Shanshan Lin
- Rimeng Chen
Institutions
- Zhaoqing University (CN)
- Huazhong Agricultural University (CN)
- Hubei Provincial Water Resources and Hydropower Planning Survey and Design Institute (CN)
- Shanghai Zhangjiang Laboratory (CN)
- ZheJiang Institute For Food and Drug Control (CN)
Publication Details
- Journal
- Metabolites
- Published
- 2025-05-23
- DOI
- https://doi.org/10.3390/metabo15060349
- Citations
- 3
- Primary Topic
- Aquaculture disease management and microbiota
- Type
- article
- Field-Weighted Citation Impact
- 2.39