Addressing Subgroup-Specific Treatment Effects to Avoid Inefficient Care: The Conflict Between Statistical and Health Economic Analyses

When subgroup heterogeneity is known, ignoring subgroups or taking a statistically guided approach will result in suboptimal reimbursement decisions and thus fail to optimize societal benefits. Therefore, subgroup-specific cost-effectiveness analyses should be informed by all available evidence of subgroup differences.

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Journal
Value in Health
Published
2025-05-23
DOI
https://doi.org/10.1016/j.jval.2025.05.004
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
Field-Weighted Citation Impact
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article

Addressing Subgroup-Specific Treatment Effects to Avoid Inefficient Care: The Conflict Between Statistical and Health Economic Analyses

Hendrik Koffijberg, Gerjon Hannink, Sopany Saing, H Amarens Geuzinge
Value in Health
Health Systems, Economic Evaluations, Quality of Life
article

Addressing Subgroup-Specific Treatment Effects to Avoid Inefficient Care: The Conflict Between Statistical and Health Economic Analyses

Hendrik Koffijberg, Gerjon Hannink, Sopany Saing, H Amarens Geuzinge
article en

Abstract

When subgroup heterogeneity is known, ignoring subgroups or taking a statistically guided approach will result in suboptimal reimbursement decisions and thus fail to optimize societal benefits. Therefore, subgroup-specific cost-effectiveness analyses should be informed by all available evidence of subgroup differences.

Value in HealthVol. 28(8)
Radboud University Nijmegen (NL), Radboud University Medical Center (NL), Zorginstituut Nederland (NL)
Reduced inequalities
Openalex Percentile: Top 84%
Health Systems, Economic Evaluations, Quality of Life
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