Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis
While the glycerine-containing emollient reduced skin dryness, it had no impact on barrier function. In contrast, MVE + GL improved the physical integrity of the barrier and reduced the sensitivity of the skin.
Authors
- John Chittock (ORCID: https://orcid.org/0000-0002-1595-7441)
- Kirsty Brown (ORCID: https://orcid.org/0000-0003-1410-4532)
- Michael J. Cork (ORCID: https://orcid.org/0000-0003-4428-2428)
- Simon G. Danby (ORCID: https://orcid.org/0000-0001-7363-140X)
- Paul Andrew (ORCID: https://orcid.org/0000-0002-9763-6413)
- Samuel F. Williams (ORCID: https://orcid.org/0000-0002-1296-0098)
- Anna Poyner
- Abigail Pinnock
Institutions
- Royal Hallamshire Hospital (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Sheffield Children's NHS Foundation Trust (GB)
- Sheffield Children's Hospital (GB)
- University of Sheffield (GB)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1093/bjd/ljaf200
- Citations
- 8
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 16.04
Funders
- Astellas Pharma