P18. The Impact of Oncoplastic Reduction Mammoplasty on Timing of Adjuvant Radiation

PURPOSE: While oncoplastic reduction mammoplasty has benefits over lumpectomy for the treatment of breast cancer, complications are reported up to 50%. This raises the concern that complications may delay adjuvant treatment. We aimed to investigate the incidence and impact of complications after oncoplastic reduction on timing to adjuvant radiation therapy. METHODS: We performed a retrospective review of patients who underwent oncoplastic reduction mammoplasty at our urban tertiary care center between 2020-2023. Patients who received adjuvant chemotherapy, or had further surgeries prior to adjuvant radiation, were excluded. The primary outcome was timing to adjuvant radiation therapy, with a delay defined as beginning therapy 12 weeks or more after reduction. Wound healing complications were defined as infection, wound healing delay, seroma, and hematoma. RESULTS: We identified 104 patients who met inclusion criteria. Of those, 91 patients (88%) had Wise pattern incisions. 18 (17%) had superomedial pedicles and 77 (74%) had inferior pedicles. Overall wound healing complication rate was 21%. 35 patients (34%) had delayed start of their adjuvant radiation. Neither pedicle (p=0.26) nor incision type (p=0.18) were significantly associated with delayed radiation therapy. However, 49% of delays were due to wound healing problems. Patients with wound healing complications had a significantly higher rate of delayed treatment than patients without wound healing complications, at 77% compared to 22% (p<0.0001). CONCLUSION: Our study confirms that wound healing complications, although unrelated to technique, are a significant concern after oncoplastic reduction mammoplasty and that patients with wound healing complications do experience higher rates of delayed treatment.