Characterization of fibroblast-like synoviocytes from the synovial fluid of patients affected by juvenile idiopathic arthritis
FLSs from the SF of JIA patients display a phenotype that has pro-inflammatory, rather than tissue-disruptive, activity; this is similar to what is observed in cells from the sublining region of the SM in adult arthritis patients. In addition, they show chondrogenic ability, indicating the potential for SF-FLSs as an in vitro model for chondrocytes.
Authors
- Federica Raggi (ORCID: https://orcid.org/0000-0002-6089-1752)
- Alessandro Consolaro (ORCID: https://orcid.org/0000-0002-0065-7614)
- Francesca Ridella
- Ignazia Prigione (ORCID: https://orcid.org/0000-0002-0877-6255)
- Simone Pelassa (ORCID: https://orcid.org/0000-0003-3751-3558)
- Marco Gattorno (ORCID: https://orcid.org/0000-0003-0704-1916)
- Maria Carla Bosco (ORCID: https://orcid.org/0000-0003-1857-7193)
- Angelo Ravelli
Institutions
- Istituto Giannina Gaslini (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1093/rheumatology/keaf266
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Ministero della Salute