Comprehensive genomic identification and functional analysis of bHLH transcription factors in Ganoderma lucidum
Compared to plants, <i>G. lucidum</i> harbored a small number of <i>bHLH</i> members but all high expression in any stages. Additionally, <i>GlbHLH5</i> and <i>GlbHLH7</i> with the highest expression among <i>GlbHLHs</i> showed activation in regulating the biosynthesis of GA. These results provide a theoretical reference for further research on ganoderic acid regulation in <i>G. lucidum</i>, and thereby providing a molecular foundation for enhancing ganoderic acid yield to optimize the medicinal value of <i>G. lucidum.</i>
Authors
- Wenxiao Chen (ORCID: https://orcid.org/0000-0001-8852-675X)
- Shasha Zhou (ORCID: https://orcid.org/0000-0003-0396-9450)
- Jun Li (ORCID: https://orcid.org/0000-0002-1406-2734)
- Xuewen Zhu
- Yaolei Mi
- Wei Sun (ORCID: https://orcid.org/0000-0002-9923-7328)
- Zhenhao Li (ORCID: https://orcid.org/0000-0002-8173-9450)
- Jing Xu (ORCID: https://orcid.org/0009-0002-5571-7079)
- Shuang‐Cheng Ma (ORCID: https://orcid.org/0000-0002-2503-806X)
- Yupeng Du
- Ying Wang (ORCID: https://orcid.org/0000-0002-2571-9367)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China Banking Regulatory Commission (CN)
- State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation (CN)
- Buchang Pharma (China) (CN)
- Northeast Forestry University (CN)
Publication Details
- Journal
- Chinese Herbal Medicines
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1016/j.chmed.2025.05.005
- Citations
- 1
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Science and Technology Development Fund
- China Academy of Chinese Medical Sciences
- National Key Research and Development Program of China
- Natural Science Foundation of Zhejiang Province