Short-interval interhemispheric inhibition does not originate from the motor hotspot
Findings demonstrate that the TMS-based association-method for source-space mapping enables physiological investigation of the distinct neuronal populations that give rise to interhemispheric inhibition of the contralateral motor cortex versus motor evoked potentials in contralateral hand muscles. SIHI can be more effectively elicited by targeting the coldspot rather than the hotspot, a potentially relevant distinction when aiming to modify interhemispheric neural communication, e.g., in stroke rehabilitation.
Authors
- Gábor Kozák (ORCID: https://orcid.org/0000-0002-3473-9351)
- David Emanuel Vetter (ORCID: https://orcid.org/0000-0002-0520-8535)
- Andreas Jooß (ORCID: https://orcid.org/0000-0002-6387-5571)
- Tuomas P. Mutanen (ORCID: https://orcid.org/0000-0002-5995-8307)
- Ulf Ziemann (ORCID: https://orcid.org/0000-0001-8372-3615)
Institutions
- Hertie Institute for Clinical Brain Research (DE)
- University of Tübingen (DE)
- Aalto University (FI)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1016/j.brs.2025.05.115
- Citations
- 1
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- European Commission
- Academy of Finland
- Tekniikan Edistämissäätiö
- Horizon 2020 Framework Programme
- European Research Council