Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023)

<i>Seoul orthohantavirus</i> (SEOV) and pathogenic leptospires, two zoonotic agents causing similar symptoms in humans, were investigated in rat populations across several neighborhoods in Bamako, Mali. SEOV seroprevalence in brown rats (<i>Rattus norvegicus</i>) reached 14.8 %, while no infection was detected in black rats (<i>Rattus rattus)</i>. Pathogenic leptospires were found in 8.7 % of brown rats, with significant inter-neighborhood variations, while only one black rat tested positive. Viral genetic analyses suggested that SEOV strains circulating in Bamako may result from a reassortment between two SEOV lineages. These findings highlight the widespread distribution of SEOV and the localized presence of pathogenic leptospires in Bamako, emphasizing the role of brown rats as reservoirs. These results can guide municipal authorities in implementing rodent control and prevention strategies to mitigate associated public health risks in Bamako.

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Publication Details

Journal
One Health
Published
2025-05-23
DOI
https://doi.org/10.1016/j.onehlt.2025.101085
Citations
1
Primary Topic
Viral Infections and Vectors
Type
article
Field-Weighted Citation Impact
1.40
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article

Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023)

Caroline Tatard, Solimane Ag Atteynine, Aurélia Kwasiborski, Juan Garona et al.
1 citations
One Health
Viral Infections and Vectors
1.40
article

Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023)

Caroline Tatard, Solimane Ag Atteynine, Aurélia Kwasiborski, Juan Garona, Guillaume Castel, Christophe Diagne, Virginie Sauvage, Carine Brouat, Nathalie Charbonnel, Véronique Hourdel, Philippe Gauthier, Laurent Granjon, Valérie Caro, Anick Bérard, A Eusebe
article en
1 citations

Abstract

<i>Seoul orthohantavirus</i> (SEOV) and pathogenic leptospires, two zoonotic agents causing similar symptoms in humans, were investigated in rat populations across several neighborhoods in Bamako, Mali. SEOV seroprevalence in brown rats (<i>Rattus norvegicus</i>) reached 14.8 %, while no infection was detected in black rats (<i>Rattus rattus)</i>. Pathogenic leptospires were found in 8.7 % of brown rats, with significant inter-neighborhood variations, while only one black rat tested positive. Viral genetic analyses suggested that SEOV strains circulating in Bamako may result from a reassortment between two SEOV lineages. These findings highlight the widespread distribution of SEOV and the localized presence of pathogenic leptospires in Bamako, emphasizing the role of brown rats as reservoirs. These results can guide municipal authorities in implementing rodent control and prevention strategies to mitigate associated public health risks in Bamako.

One HealthVol. 20
Centre de Coopération Internationale en Recherche Agronomique pour le Développement (FR), Institut Pasteur (FR), Université de Montpellier (FR), Université Paris Cité (FR), Institut Agro Montpellier (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Institut d'Économie Rurale (ML), Institut Agro Montpelier (FR), Institut de Recherche pour le Développement (FR), L'Institut Agro (FR)
Zero hunger
Openalex Percentile: Top 20%
Viral Infections and Vectors
1.40
DOIOpen Access PDFOpenAlex
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