Integration of cuproptosis-related gene signatures in stomach adenocarcinoma: implications for prognostic prediction and therapeutic strategies in cancer drug resistance

This study underscores the importance of cuproptosis-related genes, particularly FDX1, in the prognosis and therapeutic response of STAD. By integrating molecular features with clinical data, we offer insights into the potential for overcoming drug resistance in cancer therapy. These findings lay the groundwork for future research into targeted treatments that modulate cuproptosis, offering a novel approach to tackling tumor progression and resistance in STAD.

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Publication Details

Journal
Discover Oncology
Published
2025-05-23
DOI
https://doi.org/10.1007/s12672-025-02740-8
Citations
1
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
1.52

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article

Integration of cuproptosis-related gene signatures in stomach adenocarcinoma: implications for prognostic prediction and therapeutic strategies in cancer drug resistance

Yun Xu, Xiu Yuan, Peng Shi, Xin Zuo et al.
1 citations
Discover Oncology
Ferroptosis and cancer prognosis
1.52
article

Integration of cuproptosis-related gene signatures in stomach adenocarcinoma: implications for prognostic prediction and therapeutic strategies in cancer drug resistance

Yun Xu, Xiu Yuan, Peng Shi, Xin Zuo, Youchun Lei, Shan Ou, Qian Li
article en
1 citations

Abstract

This study underscores the importance of cuproptosis-related genes, particularly FDX1, in the prognosis and therapeutic response of STAD. By integrating molecular features with clinical data, we offer insights into the potential for overcoming drug resistance in cancer therapy. These findings lay the groundwork for future research into targeted treatments that modulate cuproptosis, offering a novel approach to tackling tumor progression and resistance in STAD.

Discover OncologyVol. 16(1)
First People's Hospital of Chongqing (CN)
Chongqing Municipal Education Commission
Good health and well-being
Openalex Percentile: Top 18%
Ferroptosis and cancer prognosis
1.52
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