Integration of cuproptosis-related gene signatures in stomach adenocarcinoma: implications for prognostic prediction and therapeutic strategies in cancer drug resistance
This study underscores the importance of cuproptosis-related genes, particularly FDX1, in the prognosis and therapeutic response of STAD. By integrating molecular features with clinical data, we offer insights into the potential for overcoming drug resistance in cancer therapy. These findings lay the groundwork for future research into targeted treatments that modulate cuproptosis, offering a novel approach to tackling tumor progression and resistance in STAD.
Authors
- Yun Xu (ORCID: https://orcid.org/0000-0003-1219-5549)
- Xiu Yuan
- Peng Shi (ORCID: https://orcid.org/0000-0001-8218-586X)
- Xin Zuo
- Youchun Lei
- Shan Ou
- Qian Li (ORCID: https://orcid.org/0000-0002-9919-4655)
Institutions
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1007/s12672-025-02740-8
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Chongqing Municipal Education Commission