Neurofilament light chain as a biomarker to indicate early activation of cerebral disease in boys with adrenoleukodystrophy
As far as we are aware, this is the first report highlighting that a bloodborne biomarker, plasma NfL, could potentially be used as a concomitant indicator of cerebral disease initiation, thus simplifying surveillance for cerebral ALD.
Authors
- Daniel J. Loes (ORCID: https://orcid.org/0000-0001-7661-3442)
- David Nascene (ORCID: https://orcid.org/0000-0002-2468-7359)
- Troy C. Lund (ORCID: https://orcid.org/0000-0001-9174-8919)
- Paul J. Orchard (ORCID: https://orcid.org/0000-0001-9426-1292)
- Ashish O. Gupta
Institutions
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1038/s43856-025-00915-6
- Citations
- 3
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 3.96