Inhibition of hippocampal or thalamic inputs to the nucleus accumbens reverses stress-induced alterations in dopamine system function
Taken together, these results suggest that increased coherence between the PVT and NAc, following stress, may contribute to psychosis-like symptoms but targeting either the PVT or vHipp may be viable options for the treatment of comorbid psychosis related to PTSD.
Authors
- Daniel J. Lodge (ORCID: https://orcid.org/0000-0002-6772-1748)
- Angela M. Boley (ORCID: https://orcid.org/0000-0003-0253-1481)
- Hannah B. Elam (ORCID: https://orcid.org/0000-0002-6106-4011)
- Nadine Delerue-Le Belle
- Alexandra M. McCoy (ORCID: https://orcid.org/0000-0002-8449-7717)
- Olivia J Yang (ORCID: https://orcid.org/0000-0002-9564-417X)
Institutions
- College of Wooster (US)
- The University of Texas at San Antonio Health Science Center (US)
- Vanderbilt University (US)
- Murphy Oil Corporation (United States) (US)
- South Texas Veterans Health Care System (US)
- Vanderbilt Health (US)
Publication Details
- Journal
- The International Journal of Neuropsychopharmacology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1093/ijnp/pyaf034
- Citations
- 3
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.73
Funders
- U.S. Department of Veterans Affairs
- National Institutes of Health