Sex-specific impact of polycyclic aromatic hydrocarbons and metals on renal function in U.S. adults: Mediating roles of inflammation, oxidative stress and aging
The study reveals a significant association between PAHs and HMs mixtures and CKD in the US population, with females being particularly susceptible. Biological aging emerges as a primary mediator in this relationship. Further prospective cohort studies are required to validate these findings.
Authors
- Qiang He (ORCID: https://orcid.org/0000-0003-2434-1275)
- Yue Huang (ORCID: https://orcid.org/0009-0004-9139-8161)
- Qi Liu (ORCID: https://orcid.org/0000-0001-6273-9351)
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.118380
- Citations
- 5
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 6.00