Thyroid Storm: A Case Report

Thyroid pathology is quite common worldwide. Thyroid storm is a severe form of hyperthyroidism, particularly in Graves' disease, which is rare. It is in association with various triggering factors (therapy discontinuation, infections, surgical interventions) and can lead to multiorgan dysfunction, particularly liver and cardiovascular injury. Prompt diagnosis and early therapy are fundamental to solving the thyroid storm and its complications. Multiple therapies are needed for adjustment according to the particular case, including the use of synthetic antithyroid drugs, beta-blockers, corticosteroids, and supportive therapies, depending on the systems affected. This article reports a case of long-standing Graves' disease that culminated in an episode of thyroid storm with multiorgan dysfunction (45 points on the Burch-Wartofsky point scale), representing a diagnostic challenge. Multiple therapies were needed to reach the euthyroid state, after which there was a complete resolution of the entire condition.

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Publication Details

Journal
Cureus
Published
2025-05-23
DOI
https://doi.org/10.7759/cureus.84694
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Thyroid Storm: A Case Report

Frederico Trigueiros, Ana Alves Cardoso, José Rocha, Cristiano Pinto dos Santos et al.
Cureus
Thyroid Disorders and Treatments
article

Thyroid Storm: A Case Report

Frederico Trigueiros, Ana Alves Cardoso, José Rocha, Cristiano Pinto dos Santos, Ana Filipa Vassalo
article en

Abstract

Thyroid pathology is quite common worldwide. Thyroid storm is a severe form of hyperthyroidism, particularly in Graves' disease, which is rare. It is in association with various triggering factors (therapy discontinuation, infections, surgical interventions) and can lead to multiorgan dysfunction, particularly liver and cardiovascular injury. Prompt diagnosis and early therapy are fundamental to solving the thyroid storm and its complications. Multiple therapies are needed for adjustment according to the particular case, including the use of synthetic antithyroid drugs, beta-blockers, corticosteroids, and supportive therapies, depending on the systems affected. This article reports a case of long-standing Graves' disease that culminated in an episode of thyroid storm with multiorgan dysfunction (45 points on the Burch-Wartofsky point scale), representing a diagnostic challenge. Multiple therapies were needed to reach the euthyroid state, after which there was a complete resolution of the entire condition.

CureusVol. 17(5)
Associacao Protectora dos Diabeticos de Portugal (PT), Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Hospital de Santa Maria (PT)
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Openalex Percentile: Top 84%
Thyroid Disorders and Treatments
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