Association between eGDR and accelerated aging: the mediating role of ePWV
Reduced insulin sensitivity, indicated by low eGDR, is a significant risk factor for accelerated aging. Vascular aging, measured by ePWV, mediates part of this relationship. These findings highlight the importance of monitoring insulin sensitivity and vascular health to mitigate aging and age-related health risks.
Authors
- Shun Lü (ORCID: https://orcid.org/0000-0001-8833-7262)
- Yujun Xiong (ORCID: https://orcid.org/0000-0001-9915-6723)
- Tian Lv (ORCID: https://orcid.org/0000-0002-9580-9990)
- Ди Шао (ORCID: https://orcid.org/0000-0002-1485-2074)
- Xiangda Meng (ORCID: https://orcid.org/0000-0002-0251-8095)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Wenzhou Medical University (CN)
- University of Chicago Medical Center (US)
- Ningbo No. 2 Hospital (CN)
- Peking University People's Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1186/s13098-025-01734-4
- Citations
- 4
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 5.55
Funders
- Fudan University