Deploying AI to Better Suss Out HER2 Status

Findings from a multinational study suggest that adding an AI-integrated platform to training masterclasses for pathologists boosts their accuracy in classifying HER2-stained breast cancer samples, particularly when it comes to pinpointing “low” and “ultralow” categories. Incorporating AI assistance also appears to reduce the risk of HER2-null mislabeling, which would otherwise deny patients access to potentially beneficial targeted therapies.

Publication Details

Journal
Cancer Discovery
Published
2025-01-01
DOI
https://doi.org/10.1158/2159-8290.cd-nw2025-0047
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
0.00
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article

Deploying AI to Better Suss Out HER2 Status

Cancer Discovery
Radiomics and Machine Learning in Medical Imaging
article

Deploying AI to Better Suss Out HER2 Status

article en

Abstract

Findings from a multinational study suggest that adding an AI-integrated platform to training masterclasses for pathologists boosts their accuracy in classifying HER2-stained breast cancer samples, particularly when it comes to pinpointing “low” and “ultralow” categories. Incorporating AI assistance also appears to reduce the risk of HER2-null mislabeling, which would otherwise deny patients access to potentially beneficial targeted therapies.

Cancer Discovery
Openalex Percentile: Top 82%
Radiomics and Machine Learning in Medical Imaging
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Deploying AI to Better Suss Out HER2 Status · Cancer Discovery (2025) | TGRS Research Map | TGRS