Impact of prophylactic cranial irradiation on survival in extensive-stage small cell lung cancer receiving first-line chemoimmunotherapy: a propensity score-matched study
PCI did not improve OS in ES-SCLC patients receiving first-line chemoimmunotherapy, while it may confer a survival benefit for patients who achieve remission following chemoimmunotherapy. In addition, PCI significantly reduced the incidence of brain metastases. These findings warrant further randomized studies for verification.
Authors
- Hui Li (ORCID: https://orcid.org/0000-0001-7145-4681)
- Yun Fan (ORCID: https://orcid.org/0000-0003-1755-0175)
- Wanchen Zhai (ORCID: https://orcid.org/0009-0006-5712-4524)
- Siqi Zhou (ORCID: https://orcid.org/0009-0000-5436-1256)
- Qian Zhang (ORCID: https://orcid.org/0000-0001-5975-9781)
Institutions
- Zhejiang Chinese Medical University (CN)
- Chinese Academy of Sciences (CN)
- Zhejiang Cancer Hospital (CN)
Publication Details
- Journal
- Therapeutic Advances in Medical Oncology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1177/17588359251341158
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00