Serum Cytokine 6, 10 and α-Tumour Necrosis Factor Levels in Alzheimer’s Disease Subjects Treated with Donepezil Plus Vitamin B12

We conclude that serum Cyto-6, Cyto-10, and α-TNF play an inflammatory role in Alzheimer's disease progression. Combined therapy of donepezil and VB12 supplement showed a beneficial effect in reducing inflammation. This study might benefit further research along with molecular follow-up studies for development of novel therapeutic strategies in Alzheimer's disease.

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Publication Details

Journal
Neurology India
Published
2025-05-01
DOI
https://doi.org/10.4103/neuroindia.ni_1615_20
Citations
1
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
1.16
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article

Serum Cytokine 6, 10 and α-Tumour Necrosis Factor Levels in Alzheimer’s Disease Subjects Treated with Donepezil Plus Vitamin B12

Vinayak Kale, Neelam Yeram, Leela Abichandani, Shubhangi M. Dalvi et al.
1 citations
Neurology India
Alzheimer's disease research and treatments
1.16
article

Serum Cytokine 6, 10 and α-Tumour Necrosis Factor Levels in Alzheimer’s Disease Subjects Treated with Donepezil Plus Vitamin B12

Vinayak Kale, Neelam Yeram, Leela Abichandani, Shubhangi M. Dalvi, Kamlesh Jagiasi, Ranjit Mankeshwar, Vinayak Patil
article en
1 citations

Abstract

We conclude that serum Cyto-6, Cyto-10, and α-TNF play an inflammatory role in Alzheimer's disease progression. Combined therapy of donepezil and VB12 supplement showed a beneficial effect in reducing inflammation. This study might benefit further research along with molecular follow-up studies for development of novel therapeutic strategies in Alzheimer's disease.

Neurology IndiaVol. 73(3)
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals (IN)
Good health and well-being
Openalex Percentile: Top 22%
Alzheimer's disease research and treatments
1.16
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