Postoperative Hyperglycemia with Ketosis Sans Acidemia in a Child Immediately Following Fourth Ventricular Medulloblastoma Resection: Anesthetic Concerns and Intensive Care Management

Postoperative hyperglycemia with ketosis immediately following fourth ventricular medulloblastoma surgery for a non-diabetic child with normal intraoperative blood glucose, is an uncommon clinical entity, and has seldom been reported in the literature. We present the management of this rare complication in a child. Surgical manipulation in and around the fourth ventricle and brainstem region may have disrupted central energy metabolic control involving the brain-islet axis, leading to impaired glucose homeostasis. Tumor's molecular characteristics may have also contributed to altered glucose metabolism. We emphasize the importance of being aware of this rare complication for their safe management.

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Journal
Neurology India
Published
2025-05-01
DOI
https://doi.org/10.4103/neurol-india.neurol-india-d-24-00159
Primary Topic
Neuroblastoma Research and Treatments
Type
article
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article

Postoperative Hyperglycemia with Ketosis Sans Acidemia in a Child Immediately Following Fourth Ventricular Medulloblastoma Resection: Anesthetic Concerns and Intensive Care Management

Ranganatha Praveen, Manikandan Sethuraman, Jeeva George, Arvin Ahuja et al.
Neurology India
Neuroblastoma Research and Treatments
article

Postoperative Hyperglycemia with Ketosis Sans Acidemia in a Child Immediately Following Fourth Ventricular Medulloblastoma Resection: Anesthetic Concerns and Intensive Care Management

Ranganatha Praveen, Manikandan Sethuraman, Jeeva George, Arvin Ahuja, Ajay P. Hrishi
article en

Abstract

Postoperative hyperglycemia with ketosis immediately following fourth ventricular medulloblastoma surgery for a non-diabetic child with normal intraoperative blood glucose, is an uncommon clinical entity, and has seldom been reported in the literature. We present the management of this rare complication in a child. Surgical manipulation in and around the fourth ventricle and brainstem region may have disrupted central energy metabolic control involving the brain-islet axis, leading to impaired glucose homeostasis. Tumor's molecular characteristics may have also contributed to altered glucose metabolism. We emphasize the importance of being aware of this rare complication for their safe management.

Neurology IndiaVol. 73(3)
Sree Chitra Thirunal Institute for Medical Sciences and Technology (IN), Caritas Hospital (IN)
Good health and well-being
Openalex Percentile: Top 81%
Neuroblastoma Research and Treatments
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Postoperative Hyperglycemia with Ketosis Sans Acidemia in a Child Immediately Following Fourth Ventricular Medulloblastoma Resection: Anesthetic Concerns and Intensive Care Management — Ranganatha Praveen, Manikandan Sethuraman, et al. · Neurology India (2025) | TGRS Research Map | TGRS