7-T MRI-based surrogate for histopathology examination of liver fibrosis
Using the newly developed MRI-METAVIR score, 7-T MRI data strongly correlated with histopathology, achieving excellent agreement and accuracy. 7-T MRI accurately differentiated advanced from minimal liver fibrosis. 7-T MRI visualises liver micro-architecture, enabling pathology-like, noninvasive three-dimensional imaging.
Authors
- Valérie Vilgrain (ORCID: https://orcid.org/0000-0002-3568-7725)
- Aurélie Bèaufrere (ORCID: https://orcid.org/0000-0002-0206-058X)
- Chrystelle Po (ORCID: https://orcid.org/0000-0001-9785-9572)
- Thomas F. Baumert (ORCID: https://orcid.org/0000-0002-8864-2168)
- B. Gallix (ORCID: https://orcid.org/0000-0003-0050-8608)
- Jérémy Dana (ORCID: https://orcid.org/0000-0003-0352-4128)
- Valérie Paradis (ORCID: https://orcid.org/0000-0003-3142-3762)
- Patrick Pessaux (ORCID: https://orcid.org/0000-0001-5635-7437)
- Antonin Fattori (ORCID: https://orcid.org/0000-0002-0249-4935)
- Aïna Venkatasamy (ORCID: https://orcid.org/0000-0003-0608-2353)
Institutions
- Hôpital américain de paris (FR)
- Centre National de la Recherche Scientifique (FR)
- Institut national de recherche en sciences et technologies du numérique (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Hôpital Beaujon (FR)
- University Medical Center Freiburg (DE)
- McGill University Health Centre (CA)
- Paris Cardiovascular Research Center (FR)
- Hôpitaux Universitaires de Strasbourg (FR)
- Institut de Chirurgie Guidée par l'Image (FR)
- Hôpital Civil, Strasbourg (FR)
- McGill University (CA)
- Université de Strasbourg (FR)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1186/s41747-025-00589-8
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- European Commission
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Université de Strasbourg
- Fondation ARC pour la Recherche sur le Cancer
- Centre National de la Recherche Scientifique
- HORIZON EUROPE European Research Council