Single-Cell RNA Sequencing of the Primary Visual Cortex in Mice With Optic Nerve Injury
This study generates an atlas of the V1 region of the mouse brain, highlighting the role of astrocytes and microglia in the damage changes in the V1 region after ONC, and suggesting Ptgds and Cryab as potential targets to reduce neuroinflammation.
Authors
- Qiyue Hu (ORCID: https://orcid.org/0009-0001-1701-8608)
- Weiting Zeng
- Minbin Yu
- Deling Li (ORCID: https://orcid.org/0000-0002-4300-7136)
- Xinyi Zhang (ORCID: https://orcid.org/0000-0003-4101-1104)
- Liling Liu (ORCID: https://orcid.org/0000-0002-8661-2934)
- Bin Zou (ORCID: https://orcid.org/0000-0003-2898-9562)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1167/iovs.66.5.31
- Citations
- 4
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.37