Elevated Visual Crowding in <i>CRB1</i>-Associated Retinopathies: Understanding Functional Visual Deficits Using Child-Friendly Computerized Testing
This study demonstrates for the first time that individuals with CRB1 retinopathy exhibit elevated crowding in their foveal vision compared with controls. Measuring crowding offers valuable insights into understanding functional visual deficits in CRB1 retinopathy and could be a useful metric for monitoring disease progression and treatment outcomes in inherited retinal diseases.
Authors
- Ana Catalina Rodriguez-Martinez (ORCID: https://orcid.org/0000-0003-0412-9744)
- Vijay Tailor (ORCID: https://orcid.org/0000-0002-1254-3462)
- Bethany E. Higgins (ORCID: https://orcid.org/0000-0002-4530-6156)
- Pete R. Jones (ORCID: https://orcid.org/0000-0001-7672-8397)
- Tessa M. Dekker (ORCID: https://orcid.org/0000-0002-3616-2859)
- John A. Greenwood (ORCID: https://orcid.org/0000-0002-6184-0818)
- Mariya Moosajee (ORCID: https://orcid.org/0000-0003-1688-5360)
- Robert Henderson (ORCID: https://orcid.org/0000-0002-5250-6404)
Institutions
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- St George's, University of London (GB)
- Great Ormond Street Hospital (GB)
- The Francis Crick Institute (GB)
- Moorfields Eye Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1167/iovs.66.5.32
- Citations
- 1
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Institute for Health and Care Research
- Moorfields Eye Hospital NHS Foundation Trust
- Moorfields Eye Charity