Simultaneous <scp> T <sub>1</sub> </scp> , <scp> T <sub>2</sub> </scp> , and T <sub>1ρ</sub> mapping of the myocardium using cardiac <scp>MR</scp> fingerprinting with a deep image prior reconstruction
The proposed T<sub>1ρ</sub>-cMRF sequence using DIP reconstruction enables simultaneous quantification of T<sub>1</sub>, T<sub>2</sub>, and T<sub>1ρ</sub> with decreased coefficient of variation compared to low-rank reconstruction. Simulation and phantom studies show good agreement with references. In vivo measurements were made in healthy subjects, and areas of contrast enhancement in patients showed elevated T<sub>2</sub> and T<sub>1ρ</sub> relative to remote myocardium.
Authors
- Steven Swanson (ORCID: https://orcid.org/0000-0002-5896-1037)
- Chaitanya Madamanchi (ORCID: https://orcid.org/0000-0003-4971-0110)
- Gastão Cruz (ORCID: https://orcid.org/0000-0002-7397-9104)
- Nicole Seiberlich (ORCID: https://orcid.org/0000-0002-8356-5407)
- Jesse Hamilton (ORCID: https://orcid.org/0000-0002-4463-481X)
- Venkatesh Locharla Murthy (ORCID: https://orcid.org/0000-0002-7901-1321)
- Sydney Janet Kaplan (ORCID: https://orcid.org/0000-0003-2580-3232)
Institutions
- University of Michigan (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1002/mrm.30580
- Citations
- 1
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- American Heart Association
- Division of Cancer Prevention, National Cancer Institute
- Siemens Healthineers
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases