Genome diversity of SARS-CoV-2 lineages associated with vaccination breakthrough infections in Addis Ababa, Ethiopia
The findings emphasize the need for continuous genomic surveillance and regular vaccine updates to address emerging SARS-CoV-2 variants, particularly the immune-evasive XBB lineage. The high prevalence of variants like XBB.1.5 in breakthrough infection underscores the importance of adaptive vaccination strategies and next-generation vaccines to maintain efficacy. Ongoing monitoring of variant dynamics is crucial for informed public health responses, strengthening pandemic preparedness and future outbreak prevention.
Authors
- Getnet Zeleke (ORCID: https://orcid.org/0000-0002-8896-7624)
- Yeweynshet Tesera
- Demise Mulugeta (ORCID: https://orcid.org/0000-0003-0047-1948)
- Jaleta Bulti Tura (ORCID: https://orcid.org/0000-0001-6296-1999)
- Atsbeha Gebreegziabxier
- Gemechu Tadesse Leta (ORCID: https://orcid.org/0000-0001-7623-5381)
- Abebe M Aga (ORCID: https://orcid.org/0000-0003-2268-7707)
- Abaysew Ayele
- Abraham Ali (ORCID: https://orcid.org/0000-0002-6762-2678)
- Mohammed Jemal (ORCID: https://orcid.org/0009-0001-3449-4155)
- Aderajew Mekonnen Girmay (ORCID: https://orcid.org/0000-0002-7911-4152)
- Fanos Tadesse Woldemariyam (ORCID: https://orcid.org/0000-0002-3060-7060)
- Tesfaye Gelanew (ORCID: https://orcid.org/0000-0002-0696-3786)
- Rajiha Abubeker
- Bedasa Gidisa
- Ahmed Mohammed (ORCID: https://orcid.org/0000-0002-9719-4387)
- Dereje Nigussie
- Tefera Taddele
- Gutema Bulti Tura (ORCID: https://orcid.org/0009-0008-7492-9046)
- Senait Alemayehu Beshah
- Bedasa Wagari Likasa
- Tigist Belete
Institutions
- Ethiopian Public Health Institute (ET)
- Armauer Hansen Research Institute (ET)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1186/s12879-025-11107-x
- Citations
- 5
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 6.98