Triple Synchronous Colorectal Cancer: An Extremely Rare Case Underscoring the Need for Careful Perioperative Evaluation

Synchronous colorectal cancer (SCRC) is characterized by the simultaneous occurrence of two or more primary colorectal malignancies, diagnosed either preoperatively, intraoperatively, or within six months postoperatively. The rare prevalence of SCRC makes it an uncommon scenario among colorectal malignancies. Since the majority of SCRC patients have been reported to have two concurrent malignancies, triple synchronous malignancies are extremely rare. We report the case of a 65-year-old male individual presenting with a history of abdominal pain, anemia, anorexia, and unintentional weight loss. He was diagnosed with synchronous colorectal cancer with three distinct tumors: two located in the splenic flexure and sigmoid colon, respectively, and another in the rectum that caused partial obstruction. This case highlights the importance of intraoperative evaluation and an appropriate choice of surgical intervention in colorectal cancer. The early identification and proper management of multiple colorectal cancers remain essential for better survival rates.

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Journal
Gastrointestinal Disorders
Published
2025-05-23
DOI
https://doi.org/10.3390/gidisord7020036
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
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article

Triple Synchronous Colorectal Cancer: An Extremely Rare Case Underscoring the Need for Careful Perioperative Evaluation

Melody Tran, Minh Nhat Le, T. Duong, Cong Phi Dang et al.
Gastrointestinal Disorders
Genetic factors in colorectal cancer
article

Triple Synchronous Colorectal Cancer: An Extremely Rare Case Underscoring the Need for Careful Perioperative Evaluation

Melody Tran, Minh Nhat Le, T. Duong, Cong Phi Dang, Phu Van La, Diep N. Nguyen, Dien Minh Tran, Phuc Vinh La, Vu Anh Doan
article en

Abstract

Synchronous colorectal cancer (SCRC) is characterized by the simultaneous occurrence of two or more primary colorectal malignancies, diagnosed either preoperatively, intraoperatively, or within six months postoperatively. The rare prevalence of SCRC makes it an uncommon scenario among colorectal malignancies. Since the majority of SCRC patients have been reported to have two concurrent malignancies, triple synchronous malignancies are extremely rare. We report the case of a 65-year-old male individual presenting with a history of abdominal pain, anemia, anorexia, and unintentional weight loss. He was diagnosed with synchronous colorectal cancer with three distinct tumors: two located in the splenic flexure and sigmoid colon, respectively, and another in the rectum that caused partial obstruction. This case highlights the importance of intraoperative evaluation and an appropriate choice of surgical intervention in colorectal cancer. The early identification and proper management of multiple colorectal cancers remain essential for better survival rates.

Gastrointestinal DisordersVol. 7(2)
Can Tho University (VN), University of Science and Technology - The University of Da Nang (VN)
Openalex Percentile: Top 84%
Genetic factors in colorectal cancer
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