Improved VPS4B O-GlcNAc modification triggers lipid droplets transferring from adipocytes to nasopharyngeal carcinoma cells
This study uncovers critical mechanisms of LD transfer in the TME, suggesting new therapeutic avenues in NPC.
Authors
- Feng Ju (ORCID: https://orcid.org/0000-0002-9261-1372)
- Haimeng Yin (ORCID: https://orcid.org/0000-0002-4275-0956)
- Rui Wu
- Bo You (ORCID: https://orcid.org/0000-0002-3602-5264)
- Yiwen You (ORCID: https://orcid.org/0000-0002-4171-1621)
- Yumo Han
- Qin Zhu
- Ling Yuan
- Yu Shi
- Kaiwen Zhang (ORCID: https://orcid.org/0009-0003-8126-383X)
- Tian Xia (ORCID: https://orcid.org/0000-0002-8159-1927)
- Ying Chun Shan
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Cancer & Metabolism
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1186/s40170-025-00393-3
- Citations
- 1
- Primary Topic
- Lipid metabolism and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Chinese Society of Clinical Oncology