Prognostic Value of Apolipoprotein E in Predicting One-year Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Elevated levels of ApoE were independently risk factor for one-year mortality in patients with AECOPD. Subgroup analyses revealed that the association was stronger in younger patients (<76 years) and male, as well as in those without comorbidities such as congestive heart failure or cerebrovascular disease. This suggests that ApoE may be a potential prognostic biomarker for AECOPD.
Authors
- Yuqun Li
- Liping Wei (ORCID: https://orcid.org/0000-0002-1795-8755)
- Yang Xiao (ORCID: https://orcid.org/0000-0003-3927-1839)
- Zhenxing Li (ORCID: https://orcid.org/0009-0004-2256-4250)
- Qilan Wu
Institutions
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/copd.s512096
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangzhou Medical University
- Natural Science Foundation of Guangdong Province