A Prospective Trial With Ketoconazole Induction Therapy and Octreotide Maintenance Treatment for Cushing's Disease
Sequential treatment with ketoconazole to lower cortisol levels followed by octreotide to maintain biochemical remission according to UFC may be effective in a subset of patients with mild CD, suggesting that cortisol-mediated suppression of SST2 expression is a reversible process.
Authors
- Leo J. Hofland (ORCID: https://orcid.org/0000-0002-4897-2197)
- Ticiana Paes (ORCID: https://orcid.org/0000-0003-3078-5200)
- Richard Abraham Feelders (ORCID: https://orcid.org/0000-0003-2319-391X)
- Rob van der Pas
- Romana Teodora Netea-Maier (ORCID: https://orcid.org/0000-0002-9603-0460)
- Peter H. Bisschop (ORCID: https://orcid.org/0000-0002-3583-6567)
- Fadime Dogan
- Peter M. van Koetsveld
- Knut Erik Berge (ORCID: https://orcid.org/0009-0003-4153-6792)
Institutions
- Roger Williams Medical Center (US)
- Radboud University Nijmegen (NL)
- Providence College (US)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- NYU Langone Health (US)
- Erasmus MC Cancer Institute (NL)
- Admiraal De Ruyter Ziekenhuis (NL)
- Amsterdam University Medical Centers (NL)
- Ziekenhuis Bernhoven (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1210/jendso/bvaf089
- Citations
- 6
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.77