Observation of acute toxicity events in lung cancer patients treated concurrently with a tyrosine kinase inhibitor
Concurrent TKI therapy may contribute to radiosensitization of the esophagus during thoracic radiotherapy. However, there were no grade 4-5 toxicity outcomes, suggesting feasibility of this approach. Further investigation is warranted to determine potential complications and identify approaches to mitigate risk in multimodality therapy.
Authors
- Shuaib Juma
- Eric Ku (ORCID: https://orcid.org/0000-0002-4335-2116)
- Garrett K. Harada (ORCID: https://orcid.org/0000-0002-7024-3783)
- Misako Nagasaka (ORCID: https://orcid.org/0000-0001-5308-615X)
- Peter G. Maxim (ORCID: https://orcid.org/0000-0002-8244-2042)
- John Yeakel (ORCID: https://orcid.org/0000-0002-2895-758X)
- Steven N. Seyedin (ORCID: https://orcid.org/0000-0002-6841-968X)
- Akul Munjal
- Allen Chen (ORCID: https://orcid.org/0000-0002-4914-8802)
- Jeremy P. Harris
Institutions
- University of California, Irvine (US)
- University of California, Irvine Medical Center (US)
Publication Details
- Journal
- Cancer Treatment and Research Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.ctarc.2025.100947
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52