Assessing mutation-clinical correlations and treatment outcomes in Vietnamese non-small cell lung cancer patients

Genetic profiling in Vietnamese NSCLC patients reveals a high prevalence of actionable driver mutations, supporting the integration of routine molecular testing into NSCLC management. <i>EGFR</i>-mutated patients derive significant benefits from TKI therapy, underscoring the importance of personalized treatment strategies. Further research is needed to investigate resistance mechanisms and refine targeted therapeutic approaches.

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Publication Details

Journal
Practical Laboratory Medicine
Published
2025-05-23
DOI
https://doi.org/10.1016/j.plabm.2025.e00477
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessing mutation-clinical correlations and treatment outcomes in Vietnamese non-small cell lung cancer patients

Huu Tam Phuc Nguyen, Le Mai Trang, Quoc-Trung Lam, Huu-Huy Nguyen et al.
Practical Laboratory Medicine
Lung Cancer Treatments and Mutations
article

Assessing mutation-clinical correlations and treatment outcomes in Vietnamese non-small cell lung cancer patients

Huu Tam Phuc Nguyen, Le Mai Trang, Quoc-Trung Lam, Huu-Huy Nguyen, Anh Tuấn Nguyễn, Bang-Suong Nguyen-Thi
article en

Abstract

Genetic profiling in Vietnamese NSCLC patients reveals a high prevalence of actionable driver mutations, supporting the integration of routine molecular testing into NSCLC management. <i>EGFR</i>-mutated patients derive significant benefits from TKI therapy, underscoring the importance of personalized treatment strategies. Further research is needed to investigate resistance mechanisms and refine targeted therapeutic approaches.

Practical Laboratory MedicineVol. 45
University of Medicine and Pharmacy at Ho Chi Minh City (VN), University Medical Center HCMC (VN)
Good health and well-being
Openalex Percentile: Top 81%
Lung Cancer Treatments and Mutations
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