Zr-MOF-Derived Zirconium Oxide Nanozyme and Its Hydrogel Composite Membrane for Organophosphate Detoxification
Organophosphorus nerve agents are among the most hazardous chemical warfare agents, posing serious risks to human health. Developing efficient catalysts and composite materials for their detoxification remains a significant challenge. In this study, we present the first example of zirconium oxide (ZrO<sub><i>x</i></sub>) nanozyme derived from a zirconium-based metal-organic framework (Zr-MOF), which exhibits outstanding catalytic activity for the hydrolysis of a nerve agent simulant, dimethyl-4-nitrophenyl phosphate (DMNP). Moreover, ZrO<sub><i>x</i></sub> was incorporated into a poly(vinyl alcohol) (PVA) matrix with 1,4-diazabicyclo[2.2.2]octane (dabco) as a base, forming a hydrogel composite membrane, named ZrO<sub><i>x</i></sub>@PD. Notably, ZrOx@PD demonstrates superior catalytic efficiency for the solid-phase hydrolysis of DMNP under ambient conditions, outperforming many previously reported catalytic materials and highlighting its potential as a protective material against nerve agents.
Authors
- Xiao‐Ming Ren (ORCID: https://orcid.org/0000-0003-0848-6503)
- Hong‐Bin Luo (ORCID: https://orcid.org/0000-0002-2225-7072)
- Yangyang Liu (ORCID: https://orcid.org/0000-0002-3913-5979)
- Weijie Cai (ORCID: https://orcid.org/0000-0003-4032-3552)
- Kai-Xin Zhao
- Xinru Wu (ORCID: https://orcid.org/0009-0004-4546-4594)
- Zhi-Xing Han
Institutions
- Nanjing Tech University (CN)
- California State University Los Angeles (US)
- State Key Laboratory of Materials-Oriented Chemical Engineering
- Nanjing University (CN)
Publication Details
- Journal
- Inorganic Chemistry
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1021/acs.inorgchem.5c01454
- Citations
- 5
- Primary Topic
- Advanced Nanomaterials in Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 2.59