The First-year Outcomes of the Nationwide Neonatal CAH Screening in Türkiye: High Rate of False Positives for 21-hydroxylase Deficiency and a Higher Detection Rate of Non-classical Cases
Neonatal CAH screening facilitates early diagnosis of 21-OHD and improved patient care. Using refined cut-offs may reduce referrals six-fold and eliminate second-tier testing for 95% of infants. Ongoing evaluation can enhance the efficiency and cost-effectiveness of the screening protocol.
Authors
- Yüksel Hakan Aydoğmuş (ORCID: https://orcid.org/0000-0003-2978-8738)
- Elif Eviz (ORCID: https://orcid.org/0000-0002-8889-6811)
- Eda Mengen (ORCID: https://orcid.org/0000-0003-1597-8418)
- Büşra Gürpınar Tosun (ORCID: https://orcid.org/0000-0002-7588-9807)
- Ahmet Anık (ORCID: https://orcid.org/0000-0002-7729-7872)
- Tülay Güran (ORCID: https://orcid.org/0000-0003-2658-6866)
- Emine Çamtosun (ORCID: https://orcid.org/0000-0002-8144-4409)
- Şükran Darcan (ORCID: https://orcid.org/0000-0002-1330-6397)
- Mehmet İsakoca (ORCID: https://orcid.org/0000-0002-8496-4696)
- Müge Atar (ORCID: https://orcid.org/0000-0002-9153-8580)
- Gülay Can Yılmaz (ORCID: https://orcid.org/0000-0003-0525-1231)
- Aylin Kılınç Uğurlu (ORCID: https://orcid.org/0000-0003-1265-4952)
- Doğuş Vurallı (ORCID: https://orcid.org/0000-0002-4011-2299)
- İhsan Turan (ORCID: https://orcid.org/0000-0002-5654-247X)
- Edip Ünal (ORCID: https://orcid.org/0000-0002-9809-0977)
- Elif Yuruker (ORCID: https://orcid.org/0000-0001-9962-7249)
Institutions
- Dicle University (TR)
- Ministry of Health (TR)
- University of Health Science (KH)
- Inonu University (TR)
- Ege University (TR)
- Memorial Ankara Hospital (TR)
- Antalya Eğitim ve Araştırma Hastanesi (TR)
- Education Training And Research (US)
- Türksat (Turkey) (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Ankara Bilkent City Hospital (TR)
- Cukurova University (TR)
- Hacettepe University (TR)
- Marmara University (TR)
- Adnan Menderes University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- Journal of Clinical Research in Pediatric Endocrinology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.4274/jcrpe.galenos.2025.2024-9-11
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00