Germline Testing for Prostate Cancer Patients: Evidence‐Based Evaluation of Genes Recommended by NCCN Guidelines
Supporting statistical evidence is available for only a subset of the NCCN-recommended genes for germline testing. This evidence-based analysis may aid urologists-particularly those without specialized genetics training-in understanding germline testing for PCa risk assessment, prognosis, and treatment decision-making in clinical practice.
Authors
- Ashley E. Ross (ORCID: https://orcid.org/0000-0001-7044-9688)
- Brandon Cornell
- Lucy Lu (ORCID: https://orcid.org/0000-0002-6368-3721)
- Jim Lu (ORCID: https://orcid.org/0009-0003-0989-9817)
- Catherine Handy Marshall (ORCID: https://orcid.org/0000-0002-2653-4110)
- Huy Tran (ORCID: https://orcid.org/0000-0002-9057-060X)
- Zhuqing Shi (ORCID: https://orcid.org/0000-0001-6321-950X)
- Marta Gielzak
- Christian P. Pavlovich (ORCID: https://orcid.org/0000-0002-8532-0251)
- Valentina Engelmann
- Jun Luo
- Kirk Lin
- Qiang Wang (ORCID: https://orcid.org/0000-0002-0699-2034)
- Jianfeng Xu (ORCID: https://orcid.org/0000-0002-9419-6627)
- S. Lilly Zheng
- Jun Wei (ORCID: https://orcid.org/0000-0001-9950-0467)
- Patrick C. Walsh
- Brian T. Helfand (ORCID: https://orcid.org/0000-0002-7707-3318)
- William B. Isaacs
- Annabelle Ashworth
Institutions
- Northwestern University (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- University of Chicago (US)
- SignPath Pharma (United States) (US)
- Erie Family Health Center (US)
- Arizona Pain Specialists (US)
- Cured Foundation (US)
- Johns Hopkins Hospital (US)
- Center for Genomic Science (IT)
Publication Details
- Journal
- The Prostate
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1002/pros.24918
- Citations
- 4
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 6.07
Funders
- Ambrose Monell Foundation
- Johns Hopkins University
- NorthShore University HealthSystem