Recombinant adeno-associated virus 2-mediated miRNA-199 suppression vector alleviates dextran sulfate sodium-induced ulcerative colitis in mice
rAAV can be used as a vector to inhibit gene expression in mouse colonic tissues. In mice with colitis, the rAAV-mediated suppression of miRNA-199a-5p reduces the inflammatory response.
Authors
- Shanshan Wang (ORCID: https://orcid.org/0000-0002-7205-3844)
- Yu Zhao (ORCID: https://orcid.org/0000-0003-0831-3784)
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- Virus Research
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1016/j.virusres.2025.199588
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00