The proteomic differences and expression of fatty acid‐binding protein 6 ( <scp>FABP6</scp> ) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone
Administration of PBZ at a clinical dose of 4.4 mg/kg twice daily for 7 days may cause gastric mucosal damage. PBZ treatment increased the expression of SLC10A1 and FABP6, suggesting that early gastric mucosal injury may be linked to the bile acid pathway. Bile acids could potentially exacerbate PBZ-induced EGUS.
Authors
- Nawarus Prapaiwan (ORCID: https://orcid.org/0000-0002-6203-288X)
- Narumon Phaonakrop (ORCID: https://orcid.org/0000-0002-9272-7658)
- Parichart Tesena (ORCID: https://orcid.org/0009-0002-1681-9371)
- Phirom Prompiram (ORCID: https://orcid.org/0000-0002-4091-2544)
- Sittiruk Roytrakul (ORCID: https://orcid.org/0000-0003-3696-8390)
- Ruethaiwan Vinijkumthorn (ORCID: https://orcid.org/0009-0001-1557-1813)
- Thanapon Chotikaprakal (ORCID: https://orcid.org/0009-0007-9679-0172)
Institutions
- National Science and Technology Development Agency (TH)
- Mahidol University (TH)
- National Center for Genetic Engineering and Biotechnology (TH)
Publication Details
- Journal
- Equine Veterinary Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1111/evj.14538
- Primary Topic
- Veterinary Equine Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University