The association between insulin resistance-related markers and ASCVD with hyperuricemia: results from the 2005 to 2018 National Health and Nutrition Examination Survey

This NHANES-based study highlighted significant associations between insulin resistance indices, particularly METS-IR, TyG-WC, and TyG-WHtR, and ASCVD with hyperuricemia. Furthermore, it demonstrated the strong predictive capabilities of these indices for identifying individuals at risk for this comorbidity. These findings offer valuable insights into early detection and preventive strategies for ASCVD combined with hyperuricemia, emphasizing the practicality of these indices in clinical and public health settings.