Innate immune cell barrier-related genes inform precision prognosis in pancreatic cancer
This study established the CDRG-RSF model, a robust prognostic tool leveraging innate immune genes. UBASH3B's dual role in immune suppression and drug resistance highlights its potential for stratifying PC patients into tailored treatment groups. The findings underscore the importance of integrating machine learning with immune profiling to advance precision oncology for PC.
Authors
- Tingting Jiang (ORCID: https://orcid.org/0000-0001-8755-2147)
- Keping Xie (ORCID: https://orcid.org/0000-0001-7887-9586)
- Qiang Luo (ORCID: https://orcid.org/0000-0002-4298-1623)
- Dacheng Xie
- Xiaojia Li
Institutions
- Tongji University (CN)
- Sun Yat-sen University (CN)
- Shanghai Pulmonary Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.3389/fimmu.2025.1559373
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09