The Effect of Overcoming the Digital Divide on Middle Frontal Gyrus Atrophy in Aging Adults: Large-Scale Retrospective Magnetic Resonance Imaging Cohort Study
Older adults who overcome the DD demonstrate preserved gray matter structure and slower cognitive decline, particularly in frontotemporal regions critical for executive function. Our findings underscore that mobile digital interventions should be explored as potential cognitive decline prevention strategies.
Authors
- Yumeng Li (ORCID: https://orcid.org/0009-0002-8833-8884)
- Junying Zhang (ORCID: https://orcid.org/0000-0001-9299-0256)
- Xin Li (ORCID: https://orcid.org/0000-0001-9598-0299)
- Xinyue Zhang (ORCID: https://orcid.org/0009-0002-5724-6389)
- Zhanjun Zhang (ORCID: https://orcid.org/0000-0002-6714-3263)
- Jiaqing Sun (ORCID: https://orcid.org/0000-0002-7896-5860)
- Aiqin Zhu (ORCID: https://orcid.org/0000-0001-7634-8036)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Normal University (CN)
- Qinghai Provincial Peoples Hospital (CN)
- London School of Economics and Political Science (GB)
Publication Details
- Journal
- Journal of Medical Internet Research
- Published
- 2025-05-22
- DOI
- https://doi.org/10.2196/73360
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China