Formulation and Evaluation Poly Herbal Cream to Treat Skin Burning

Abstract; This study focuses on the formulation and evaluation of a polyherbal cream intended for the treatment of minor skin burns, incorporating natural ingredients such as Delonix regia extract, turmeric (Curcuma longa), peppermint oil, lavender oil, and honey. Each component was selected based on its well-documented medicinal properties: Delonix regia for its antiinflammatory and antioxidant activities; turmeric for its curcumin content, known for wound healing and antimicrobial effects; peppermint oil for its soothing, cooling action; lavender oil for its analgesic and skin regenerative capabilities; and honey for its antibacterial and moisturizing benefits. The ingredients were homogenously mixed into a cream base and subjected to physicochemical evaluation, including pH, viscosity, spreadability, and stability testing. The formulated polyherbal cream was then evaluated for its efficacy on minor thermal burns using in vitro and ex vivo models. Results demonstrated that the cream exhibited significant wound healing properties, reduced inflammation, and improved epithelial regeneration compared to the control. The presence of both essential oils and botanical extracts contributed synergistically to the therapeutic action, making the polyherbal formulation a promising, natural alternative for managing mild to moderate burn injuries. Further clinical testing is suggested to validate its safety and efficacy in human subjects.