Observation of the Effects of Infrapatellar Fat Pad Excision on the Inflammatory Progression of Knee Osteoarthritis in Mice
IFP excision, especially partial excision, significantly modulates the inflammatory response in KOA. Partial excision showed the most effective and balanced impact on joint stability, bone integrity, and cartilage protection, offering potential as a therapeutic approach for KOA.
Authors
- Rende Ning (ORCID: https://orcid.org/0000-0002-5355-263X)
- Shuo Yang (ORCID: https://orcid.org/0009-0007-1268-1594)
- Bizhi Tu (ORCID: https://orcid.org/0000-0003-0665-9167)
- Lingchao Kong
- Ya Li (ORCID: https://orcid.org/0000-0003-4356-7042)
- Haoyu Yao
- Peizhi Lu
Institutions
- Bengbu Medical College (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Third People's Hospital of Hefei (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/jir.s517314
- Citations
- 4
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 6.67