A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Two of 6 patients (33.3%) with SCCOHT achieved durable CR/iCR and long-term survival with ipilimumab plus nivolumab. Correlative studies to determine response and resistance markers are ongoing.

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Publication Details

Journal
Cancer Communications
Published
2025-05-22
DOI
https://doi.org/10.1002/cac2.70020
Citations
1
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.81

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article

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Tanya Pejovic, Liam Il‐Young Chung, Elad Sharon, Hye Sung Kim et al.
1 citations
Cancer Communications
Chromatin Remodeling and Cancer
0.81
article

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Tanya Pejovic, Liam Il‐Young Chung, Elad Sharon, Hye Sung Kim, Megan Othus, Charles D. Blanke, Helen X Chen, Khine Z. Win, Christopher W. Ryan, Razelle Kurzrock, Sajeve Thomas, Sandip Pravin Patel, Young Kwang Chae, Christine M. McLeod, HOWARD Z. STREICHER, William R. Robinson, Raid Aljumaily
article en
1 citations

Abstract

Two of 6 patients (33.3%) with SCCOHT achieved durable CR/iCR and long-term survival with ipilimumab plus nivolumab. Correlative studies to determine response and resistance markers are ongoing.

Cancer CommunicationsVol. 45(8)
Northwestern University (US), Tulane University (US), Orlando Health (US), Oregon Health & Science University (US), Medical College of Wisconsin (US), University of Florida Health (US), Rideout Memorial Hospital (US), University of California San Diego (US), Florida Hospital Cancer Institute (US), Comprehensive Cancer Center Vienna (AT), Temple University Hospital (US), University of California San Diego Medical Center (US), National Cancer Institute (MY), National Cancer Institute (US), New Mexico Cancer Center (US), Data Management Services (United States) (US), Cancer Institute of Florida (US), SWOG Cancer Research Network (US), Moores Cancer Center, OU Health, UC Davis Comprehensive Cancer Center, OHSU Knight Cancer Institute, University of Oklahoma Health Sciences Center (US)
Bristol-Myers Squibb, National Institutes of Health, National Cancer Institute
Good health and well-being
Openalex Percentile: Top 28%
Chromatin Remodeling and Cancer
0.81
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