Engineered Outer Membrane Vesicles for Antigen Delivery: Exploratory Study on Adjuvant Activity and Systemic Reactogenicity
While Mut4_OMVs retain potent adjuvant activity, their residual toxicity necessitates further biocompatibility optimization for safe vaccine applications.
Authors
- Yanfang Zhai (ORCID: https://orcid.org/0000-0002-0436-9089)
- Lina Zhai
- Yanchun Wang (ORCID: https://orcid.org/0000-0002-0203-7312)
- Shuli Sang
- Rui Yu (ORCID: https://orcid.org/0000-0002-6431-9737)
- Yunyun Mao (ORCID: https://orcid.org/0000-0003-4552-7669)
- Kai Li (ORCID: https://orcid.org/0000-0003-2614-0282)
- Chen Cao
- Yiyan Guan
- Qikun Ou
- Lu Lu (ORCID: https://orcid.org/0000-0001-6435-2492)
Institutions
- Guangxi Medical University (CN)
- Beijing University of Technology (CN)
Publication Details
- Journal
- Vaccines
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3390/vaccines13060552
- Citations
- 2
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.61