Neuroimaging Reader Study on Clinical Sensitivity and Specificity Using Synthetic MRI Based on MR Quantification
In this study no significant differences were found in the sensitivity and specificity of pathologic findings and accuracy of imaging findings between 3D synthetic T1-weighted and T2-weighted images and 3D conventional images. In addition, 5 blinded neuroradiologists rated 3D synthetic MR images of higher image quality than conventional 3D images.
Authors
- Swati Rane Levendovszky (ORCID: https://orcid.org/0000-0001-8863-3168)
- Thomas Snyder (ORCID: https://orcid.org/0000-0002-7567-1488)
- Patricia Cornejo (ORCID: https://orcid.org/0000-0001-5096-6047)
- John‐Paul Carpenter
- Nándor Pintér (ORCID: https://orcid.org/0000-0002-7714-143X)
- Gilbert O. Maulsby (ORCID: https://orcid.org/0009-0008-5819-3227)
- Laszlo Mechtler (ORCID: https://orcid.org/0000-0002-6105-9159)
- David M. Lefkowitz
- Evelyn Lange (ORCID: https://orcid.org/0009-0003-1738-8478)
- Jeffrey H Miller (ORCID: https://orcid.org/0000-0002-0018-2532)
- Lori Hayes
- J. B. M. Warntjes (ORCID: https://orcid.org/0000-0002-3037-4201)
- P. Johansson (ORCID: https://orcid.org/0009-0005-9809-4758)
- Kenneth F. Koral
Institutions
- West Virginia University (US)
- University of Washington (US)
- Southwestern Medical Center (US)
- Dent Neurologic Institute (US)
- Nemours Children's Health System (US)
- Phoenix Children's Hospital (US)
- Naples Anesthesia & Physician Associates (US)
- University of Washington Applied Physics Laboratory (US)
- Synthetic Biologics (United States) (US)
- IntraMedical Imaging (United States) (US)
- Nemours Children's Clinic (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3174/ajnr.a8631
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00