Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells
ATO significantly promoted ferroptosis in HCC cells, and NRF2 knockdown enhanced the cytotoxic effects of ATO.
Authors
- Mingfeng Jiang (ORCID: https://orcid.org/0000-0003-3013-4790)
- Chao Yuan (ORCID: https://orcid.org/0000-0002-4792-8266)
- Wenxia Si (ORCID: https://orcid.org/0000-0001-9380-7791)
- Duanzhuo Li
- Xin Yu (ORCID: https://orcid.org/0000-0003-0543-5567)
- 益栄 今泉 (ORCID: https://orcid.org/0009-0000-7454-7437)
- Yanli Liao
- Shengjie Liao (ORCID: https://orcid.org/0000-0003-4584-631X)
- Weibin Wu (ORCID: https://orcid.org/0000-0003-4308-0664)
- Mi Ni Huang (ORCID: https://orcid.org/0000-0002-7669-7364)
- Zhengzhen Xia
Institutions
- Guangdong Medical College (CN)
- Zhaoqing University (CN)
- The First People's Hospital of Zhaoqing (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1371/journal.pone.0322746
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Guangdong Science and Technology Department
- Department of Education of Guangdong Province